CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell‐Cell Adhesion

• Published in: Stem cells (Dayton, Ohio) Vol. 34; no. 11; pp. 2648 - 2660
• Main Authors: Liu, Jie, Qi, Yanmei, Li, Shaohua, Hsu, Shu‐Chan, Saadat, Siavash, Hsu, June, Rahimi, Saum A., Lee, Leonard Y., Yan, Chenghui, Tian, Xiaoxiang, Han, Yanling
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.11.2016
• Subjects: Assembly; Binding; Cadherins; Cardiac differentiation; Cardiomyocytes; Cell adhesion; Cell adhesion & migration; Cell interactions; Cell junctions; Cohesion; Degradation; Differentiation (biology); Disks; Embryonic stem cells; Exocyst; Gap junctions; Heart; Heart diseases; Integration; Intercalated discs; Membrane vesicles; Myocardium; N-Cadherin; Regeneration; Site-directed mutagenesis; Stem cell transplantation; Stem cells; Tethers; Embryonic stem cells; Exocyst; Intercalated discs; Cardiac differentiation

Understanding the regulation of cell‐cell interactions during the formation of compact myocardial structures is important for achieving true cardiac regeneration through enhancing the integration of stem cell‐derived cardiomyocytes into the recipient myocardium. In this study, we found that cellular...