Can neurological soft signs and neurocognitive deficits serve as a combined endophenotype for Han Chinese with bipolar disorder?

• Published in: International journal of methods in psychiatric research Vol. 32; no. 4; pp. e1970 - n/a
• Main Authors: Feng, Yingying, Song, Jia, Lin, Guorong, Qian, Hong, Feng, Li, Wang, Zongqin, Wen, Juan, Wang, Chengchen, Wang, Jiayuan, Li, Peifu, Gao, Zuohui, Wang, Xiaoli, Hu, Xiaohua
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.12.2023; Wiley
• Subjects: Bipolar disorder; Bipolar Disorder - complications; Bipolar Disorder - diagnosis; Cognition; Cognition Disorders - psychology; Cognitive ability; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - etiology; East Asian People; endophenotype; Endophenotypes; Humans; Information processing; information processing speed; Language; Motor ability; neurocognitive deficits; neurological soft signs; Neuropsychological Tests; Risk groups; Short term memory; verbal learning; working memory; neurocognitive deficits; bipolar disorder; neurological soft signs; working memory; verbal learning; endophenotype; information processing speed

Background Bipolar disorder's (BD) potential endophenotypes include neurological soft signs (NSS) and neurocognitive disorders (ND). Few research, meanwhile, has coupled NSS and ND as combined endophenotypes of BD. Object This study intends to investigate NSS and ND and compare their difference...