Physical principles of membrane remodelling during cell mechanoadaptation

• Published in: Nature communications Vol. 6; no. 1; p. 7292
• Main Authors: Kosmalska, Anita Joanna, Casares, Laura, Elosegui-Artola, Alberto, Thottacherry, Joseph Jose, Moreno-Vicente, Roberto, González-Tarragó, Víctor, Del Pozo, Miguel Ángel, Mayor, Satyajit, Arroyo, Marino, Navajas, Daniel, Trepat, Xavier, Gauthier, Nils C, Roca-Cusachs, Pere
• Format: Journal Article Publication
• Language: English
• Published: England Nature Publishing Group 15.06.2015; Nature Pub. Group
• Subjects: 92 Biology and other natural sciences; 92B Mathematical biology in general; Adaptation, Physiological - physiology; ALVEOLAR EPITHELIAL-CELLS; Animals; Biologia; Biomathematics; Cell Membrane - physiology; Cell Shape; Cell Size; Classificació AMS; DYNAMICS; Elasticity; EXOCYTOSIS; Fibroblasts - physiology; LIVING CELLS; Matemàtica aplicada a les ciències; Matemàtiques i estadística; Mice; MIGRATION; Models matemàtics; Models, Biological; Models, Theoretical; NEURONS; Osmolar Concentration; Physiology; SHAPE; STRESS; Stress, Mechanical; SURFACE-AREA REGULATION; TENSION; Àrees temàtiques de la UPC; Singapore; Spain

Biological processes in any physiological environment involve changes in cell shape, which must be accommodated by their physical envelope--the bilayer membrane. However, the fundamental biophysical principles by which the cell membrane allows for and responds to shape changes remain unclear. Here w...