Integrin Beta 1 Promotes Glioma Cell Proliferation by Negatively Regulating the Notch Pathway

• Published in: Journal of oncology Vol. 2020; no. 2020; pp. 1 - 11
• Main Authors: Yue, Zhijian, Xu, Jinyu, Chen, Chao, Zuo, Qiao, Dai, Dongwei, Zou, Chao, Min, Weijie, Li, Yanan
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2020; Hindawi; John Wiley & Sons, Inc
• Subjects: Bioinformatics; Brain cancer; Cell growth; Genes; Glioma; Ligands; Medical diagnosis; Medical prognosis; Patients; Protein expression; Proteins; United States > US; China

In this study, genes associated with the Notch signaling pathway in gliomas were analyzed using bioinformatics and in vitro experiments. The dataset GSE22772 was downloaded from the Gene-Cloud of Biotechnology Information database. Differentially expressed genes (DEGs) between short hairpin RNA (shR...