Efficacy of Drug Treatment in Obsessive–Compulsive Disorder: a Meta-Analytic Review

• Published in: British journal of psychiatry Vol. 166; no. 4; pp. 424 - 443
• Main Authors: Piccinelli, Marco, Pini, Stefano, Bellantuono, Cesario, Wilkinson, Greg
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.04.1995; RCP
• Subjects: 1-Naphthylamine - administration & dosage; 1-Naphthylamine - analogs & derivatives; 1-Naphthylamine - therapeutic use; Adjustment; Adolescent; Adult; Antidepressants; Antidepressive Agents; Anxiety; Bibliographic literature; Child; Clinical research; Clinical trials; Clomipramine; Clomipramine - administration & dosage; Clomipramine - therapeutic use; Double-Blind Method; Double-blind studies; Drug addiction; Drugs; Efficacy; Fluoxetine; Fluvoxamine; Fluvoxamine - administration & dosage; Fluvoxamine - therapeutic use; Humans; Medical treatment; Mental depression; Meta-analysis; Obsessive compulsive disorder; Obsessive-Compulsive Disorder - drug therapy; Obsessive-Compulsive neuroses; Patients; Pharmaceutical industry; Physical symptoms; Placebos; Psychiatry; Psychopharmacology; Psychosocial factors; Review Articles; Serotonin; Serotonin reuptake inhibitors; Sertraline; Suffering; Treatment; Treatment Outcome; Uptake

A review of the efficacy of antidepressant drug treatment in patients with obsessive-compulsive disorder (OCD), using a meta-analytic approach. Randomised double-blind clinical trials of antidepressant drugs, carried out among patients with OCD and published in peer-reviewed journals between 1975 an...