Lactate Dehydrogenase as a Biomarker for Prediction of Refractory Mycoplasma pneumoniae Pneumonia in Children

• Published in: Respiratory care Vol. 60; no. 10; p. 1469
• Main Authors: Lu, Aizhen, Wang, Chuankai, Zhang, Xiaobo, Wang, Libo, Qian, Liling
• Format: Journal Article
• Language: English
• Published: United States 01.10.2015
• Subjects: Adrenal Cortex Hormones - therapeutic use; Age Factors; Alanine Transaminase - blood; Aspartate Aminotransferases - blood; Biomarkers - blood; Blood Sedimentation; C-Reactive Protein - analysis; Child, Preschool; Female; Humans; Hydroxybutyrate Dehydrogenase - blood; Infant; Infant, Newborn; L-Lactate Dehydrogenase - blood; Logistic Models; Male; Mycoplasma pneumoniae; Neutrophils; Pneumonia, Mycoplasma - blood; Pneumonia, Mycoplasma - drug therapy; Predictive Value of Tests; Prospective Studies; ROC Curve; erythrocyte sedimentation rate; lactate dehydrogenase; receiver operating curve; Refractory Mycoplasma pneumoniae pneumonia; α-hydroxybutyrate dehydrogenase

Corticosteroids have been used for refractory Mycoplasma pneumoniae pneumonia and have beneficial effects. The aim of this study was to identify the biomarkers for predicting refractory M. pneumoniae pneumonia in a timely fashion to initiate steroid therapy. This was a prospective cohort study of ch...