Association study for the relationship between a haplotype or haplotype set and multiple quantitative responses

• Published in: Computational statistics & data analysis Vol. 55; no. 6; pp. 2104 - 2113
• Main Authors: Tomita, Makoto, Hashimoto, Noboru, Tanaka, Yutaka
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.06.2011; Elsevier
• Series: Computational Statistics & Data Analysis
• Subjects: Additives; Combinatorics; Combinatorics. Ordered structures; Computer simulation; Data processing; Designs and configurations; Exact sciences and technology; General topics; Genetics; Haplotype; Likelihood ratio test; Mathematical models; Mathematics; Multivariate analysis; Multivariate analysis Quantitative responses Haplotype Likelihood ratio test; Normal distribution; Numerical analysis; Numerical analysis. Scientific computation; Numerical methods in probability and statistics; Probability and statistics; Quantitative responses; Sciences and techniques of general use; Statistics; Stochasticity; Multivariate analysis; Haplotype; Likelihood ratio test; Quantitative responses; Data analysis; Statistical distribution; Gaussian distribution; Multivariate distribution; Statistical association; Numerical method; Stochastic method; Additive model; Numerical analysis; Statistical computation; Genetics; Comparative study

Though there have been several works on the analysis of the association between genotype and phenotype, little can be found for the association analysis between a haplotype or haplotype sets and multivariate quantitative responses. For example, QTLmarc is available for the analysis of multivariate r...