Construction of a Novel Immune-Related lncRNA Pair Signature with Prognostic Significance for Kidney Clear Cell Renal Cell Carcinoma

• Published in: Disease markers Vol. 2021; pp. 1 - 17
• Main Authors: Sun, Jian-Xuan, Xia, Qi-Dong, Liu, Chen-Qian, Xu, Jin-Zhou, Xun, Yang, Lu, Jun-Lin, Hu, Jia, Wang, Shao-Gang
• Format: Journal Article
• Language: English
• Published: United States Hindawi 2021; John Wiley & Sons, Inc
• Subjects: Aged; Apoptosis; Biomarkers; Biomarkers, Tumor - genetics; Cancer; Cancer therapies; Carcinoma, Renal Cell - genetics; Carcinoma, Renal Cell - immunology; Carcinoma, Renal Cell - pathology; Chemotherapy; Clear cell-type renal cell carcinoma; Female; Follow-Up Studies; Gene expression; Gene Expression Regulation, Neoplastic; Genes; Genomes; Humans; Immune system; Immunotherapy; Kidney cancer; Kidney Neoplasms - genetics; Kidney Neoplasms - immunology; Kidney Neoplasms - pathology; Lymphocytes, Tumor-Infiltrating - immunology; Male; Medical prognosis; Metastasis; Microenvironments; Middle Aged; Model testing; Patients; Prognosis; Proteins; Regression analysis; Ribonucleic acid; Risk; Risk groups; RNA; RNA, Long Noncoding - genetics; Statistical models; Subgroups; Survival; Survival analysis; Survival Rate; Transcriptome; Transcriptomes; Tumor Microenvironment; Tumors; United States > US

Background. Renal cell carcinoma (RCC) is one of the most common aggressive malignant tumors in the urinary system, among which the clear cell renal cell carcinoma (ccRCC) is the most common subtype. The immune-related long noncoding ribonucleic acids (irlncRNAs) which are abundant in immune cells a...