Increased fatigability and impaired skeletal muscle microvascular reactivity in adults with obstructive sleep apnea: a cross-sectional study

• Published in: European journal of medical research Vol. 29; no. 1; pp. 506 - 14
• Main Authors: Puri, Shipra, Aldhahi, Monira, Chin, Lisa M K, Guccione, Andrew A, Jain, Vivek, Herrick, Jeffrey E
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.10.2024; BioMed Central; BMC
• Subjects: Adult; Adults; Cross-Sectional Studies; Fatigability; Fatigue; Female; Humans; Male; Microcirculation - physiology; Microvascular reactivity; Microvessels - physiopathology; Middle Aged; Muscle Fatigue - physiology; Muscle, Skeletal - blood supply; Muscle, Skeletal - physiopathology; Muscles; Near-infrared spectroscopy; Obstructive sleep apnea; Sleep apnea syndromes; Sleep Apnea, Obstructive - physiopathology; Spectroscopy, Near-Infrared - methods; Microvascular reactivity; Fatigability; Obstructive sleep apnea; Near-infrared spectroscopy

Sympathetic nervous system hyperactivity and chronic intermittent nocturnal hypoxia in individuals with obstructive sleep apnea (OSA) predispose them to microvascular impairment, which may contribute to increased daytime muscle fatigue. This study aimed to assess microvascular reactivity of the skel...