Associations between RetNet gene polymorphisms and the efficacy of orthokeratology for myopia control: a retrospective clinical study

• Published in: Eye and vision (Novato, Calif.) Vol. 12; no. 1; p. 13
• Main Authors: Xia, Ruijing, Yu, Xiangyi, Wu, Hao, Peng, Lulu, Du, Zhenlin, Yu, Xiaoguang, Xing, Shilai, Lu, Fan, Mao, Xinjie
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.03.2025; BioMed Central; BMC
• Subjects: Anopheles; Burden test; Clinical trials; Genes; Genetic aspects; Genetic polymorphisms; Genomes; Genomics; Medical genetics; Myopia; Myopia control; Orthokeratology; Single-variant association analysis; WGS; China; Myopia control; WGS; Orthokeratology; Burden test; Single-variant association analysis

This study investigated how clinical and genetic factors impact the effectiveness of orthokeratology lenses in myopia. A retrospective clinical study was conducted with a sample of 545 children aged 8-12 years who had myopia and have initially worn orthokeratology lenses for one year. Whole-genome s...