Recanalization Treatment of Acute Ischemic Stroke Caused by Large-Artery Occlusion in the Elderly: A Comparative Analysis of “the Elderly” and “the Very Elderly”

• Published in: Disease markers Vol. 2021; pp. 3579074 - 9
• Main Authors: Wang, Qi, Zhang, Yi-Qun, Qiu, Han-Cheng, Yao, Yin-Dan, Liu, Ao-Fei, Li, Chen, Jiang, Wei-Jian
• Format: Journal Article
• Language: English
• Published: United States Hindawi 2021; Hindawi Limited
• Subjects: Administration, Intravenous; Age; Aged; Aged, 80 and over; Arterial Occlusive Diseases - complications; Arterial Occlusive Diseases - drug therapy; Arterial Occlusive Diseases - surgery; Blood clots; Blood pressure; Cardiac arrhythmia; Cerebral Arteries - pathology; Comparative analysis; Endovascular Procedures - adverse effects; Female; Health care facilities; Hemorrhage; Humans; Ischemia; Ischemic Stroke - drug therapy; Ischemic Stroke - etiology; Ischemic Stroke - mortality; Ischemic Stroke - surgery; Male; Medical imaging; Medical research; Middle Aged; Mortality; Neurosurgery; Occlusion; Older people; Patients; Retrospective Studies; Safety; Stroke; Therapy; Thrombectomy - adverse effects; Thrombolytic Therapy - adverse effects; Tissue Plasminogen Activator - administration & dosage; Tissue Plasminogen Activator - therapeutic use; Treatment Outcome; Vein & artery diseases

Objective. To assess whether the effectiveness and safety of recanalization therapy for acute ischemic stroke (AIS) caused by large-artery occlusion (LAO) differ between patients aged 60–79 years and patients aged ≥80 years. Methods. We analyzed prospective data of patients with LAO (≥60 years) who...