Metabolic profile of nicotine in subjects whose CYP2A6 gene is deleted - Yamanaka, Hiroyuki; Nakajima, Miki; Nishimura, Kiyoko; Yoshida, Ryoko; Fukami, Tatsuki; Katoh, Miki; Yokoi, Tsuyoshi (European journal of pharmaceutical sciences, 2004)
Keywords: Adult; Aryl Hydrocarbon Hydroxylases - deficiency; Aryl Hydrocarbon Hydroxylases - genetics; Aryl Hydrocarbon Hydroxylases - physiology; Biological and medical sciences; CYP2A6; Cytochrome P-450 CYP2A6; Female; Gene Deletion; General pharmacology; Humans; LC–MS/MS; Male; Medical sciences; Mixed Function Oxygenases - deficiency; Mixed Function Oxygenases - genetics; Mixed Function Oxygenases - physiology; Nicotine; Nicotine - administration & dosage; Nicotine - metabolism; Nicotine - urine; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Poor metabolizer; CYP2A6; Poor metabolizer; LC–MS/MS; Nicotine; Human; LC-MS/MS; Alkaloid; Pharmaceutical technology; Gene; Pharmacokinetics; Metabolism