Hyperuricemia prevalence in healthy subjects and its relationship with cardiovascular target organ damage

• Published in: Nutrition, metabolism, and cardiovascular diseases Vol. 31; no. 1; pp. 178 - 185
• Main Authors: Maloberti, Alessandro, Qualliu, Esmerilda, Occhi, Lucia, Sun, Jinwei, Grasso, Enzo, Tognola, Chiara, Tavecchia, Giovanni, Cartella, Iside, Milani, Martina, Vallerio, Paola, Signorini, Stefano, Brambilla, Paolo, Casati, Marco, Bombelli, Michele, Grassi, Guido, Giannattasio, Cristina
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 04.01.2021
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers - blood; cardiovascular diseases; Cardiovascular Diseases - blood; Cardiovascular Diseases - diagnosis; Cardiovascular Diseases - epidemiology; carotid arteries; Cross-Sectional Studies; disease prevalence; Female; Glomerular filtration rate; Healthy subjects; Healthy Volunteers; heart ventricle; Humans; hyperuricemia; Hyperuricemia - blood; Hyperuricemia - diagnosis; Hyperuricemia - epidemiology; Italy - epidemiology; kidney diseases; Kidney Diseases - blood; Kidney Diseases - diagnosis; Kidney Diseases - epidemiology; Male; men; Middle Aged; Prevalence; Pulse wave velocity; regression analysis; Risk Assessment; Risk Factors; Target organ damage; ultrasonography; Uric acid; Uric Acid - blood; women; Young Adult; Italy; Target organ damage; Pulse wave velocity; Healthy subjects; Uric acid; Glomerular filtration rate

Heterogeneous results have been obtained in the relationship between Uric Acid (UA) and Target Organ Damage (TOD). In the present study we sought to assess the prevalence of hyperuricemia in healthy subjects as well as the role of UA in determining TOD. We evaluated vascular, cardiac and renal TODs...