The association between allostatic load and brain: A systematic review

• Published in: Psychoneuroendocrinology Vol. 145; p. 105917
• Main Authors: Lenart-Bugla, Marta, Szcześniak, Dorota, Bugla, Błażej, Kowalski, Krzysztof, Niwa, Saya, Rymaszewska, Joanna, Misiak, Błażej
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.11.2022
• Subjects: Allostasis; Allostatic load; Brain imaging; Brain structure; Stress; Allostatic load; Brain imaging; Brain structure; Stress; Allostasis

Allostatic load (AL) refers to prolonged dysregulation related to chronic stress that affects brain regions such as the hippocampus, amygdala, and prefrontal cortex (PFC). Higher levels of AL have been associated with poor health outcomes, including psychiatric disorders, cognitive decline, and chro...