Ischemia-Modified Albumin: Origins and Clinical Implications

• Published in: Disease markers Vol. 2021; pp. 1 - 18
• Main Authors: Shevtsova, Alla, Gordiienko, Iuliia, Tkachenko, Viktoriia, Ushakova, Galyna
• Format: Journal Article
• Language: English
• Published: United States Hindawi 2021; John Wiley & Sons, Inc
• Subjects: Acidosis; Albumin; Albumins; Albumins - metabolism; Amino acids; Binding; Binding sites; Biomarkers - metabolism; Blood pressure; Cardiac stress tests; Cardiovascular disease; Cobalt; Evaluation; Fatty acids; Heavy metals; Hormones; Humans; Ischemia; Ischemia - metabolism; Myocardial ischemia; Nickel; Oxidative stress; Peptides; Plasma proteins; Proteins; Reactive oxygen species; Review; Transition metals

Albumin is one of the most abundant proteins in the body of mammals: about 40% of its pool is located in the intravascular space and the remainder is found in the interstitial space. The content of this multifunctional protein in blood is about 60-65% of total plasma proteins. A decrease in its synt...