Incomplete Urethral Duplication Associated with a Dermoid Cyst within a Vascular Hamartoma in a Female Dog

• Published in: Veterinary sciences Vol. 6; no. 2; p. 50
• Main Authors: Clancy, Chad S, Hullinger, Gordon A, Van Wettere, Arnaud J
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.05.2019; MDPI
• Subjects: Abdomen; Anemia; Bladder; Blood vessels; Bone marrow; Case Report; Clitoris; Collagen; Conflicts of interest; Cysts; Dermis; dermoid cyst; Dogs; Effusion; Epithelium; Follicles; hamartoma; Leukocytosis; Necropsy; Neoplasia; Stroma; Sweat gland; Thrombocytopenia; Urethral duplication; Urinary tract diseases; Urinary tract infections; Urogenital system; Urothelium; Veterinary medicine; dermoid cyst; hamartoma; Urethral duplication
• DOI: 10.3390/vetsci6020050
• ISSN: 2306-7381

A seven-year-old spayed female Labrador retriever presented for necropsy following an acute history of thrombocytopenia, anemia, leukocytosis and abdominal effusion. A 2 × 3 × 10 cm, cylindrical to tubular, mottled red-to-tan mass extended from the caudal pelvic cavity caudally and ventrally under the dermis along the caudal aspect of the left pelvic limb adjacent to the semimembranosus and semitendinosus musculature. Histologic examination of the mass revealed a singular central lumen lined by urothelium that multifocally transitioned into non-keratinizing, stratified squamous epithelium associated with few hair follicles and sweat glands. The lumen was surrounded by a dense collagenous stroma containing numerous, variably sized blood vessels. The combination of lesions was consistent with a diagnosis of incomplete urethral duplication associated with a dermoid cyst and vascular hamartoma. To the authors' knowledge, this is the first report of an incomplete urethral duplication associated with a dermoid cyst within a vascular hamartoma.