A mild stressor induces short-term anxiety and long-term phenotypic changes in trauma-related behavior in female rats

• Published in: Frontiers in behavioral neuroscience Vol. 17; p. 1231563
• Main Authors: Shanazz, Khadijah, Nalloor, Rebecca, Vazdarjanova, Almira
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 04.09.2023; Frontiers Media S.A
• Subjects: Animals; Anxiety; Anxiety disorders; avoidance extinction; Behavior; Behavioral Neuroscience; contextual fear conditioning; Emotional behavior; Exploratory behavior; Extinction behavior; Fear & phobias; Fear conditioning; fear extinction; Hair; LDOF; Learning; Light; Long-term effects; Post traumatic stress disorder; PTSD; Sexual dimorphism; stress history; Trauma; PTSD; avoidance extinction; contextual fear conditioning; LDOF; fear extinction; stress history
• ISSN: 1662-5153; 1662-5153
• DOI: 10.3389/fnbeh.2023.1231563

Anxiety and anxiety-influenced disorders are sexually dimorphic with women being disproportionately affected compared to men. Given the increased prevalence in women and the documented differences in anxiety and trauma behavior between male and female rats this paper sought to examine the link betwe...