Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments

• Published in: Journal of Alzheimer's disease Vol. 26; no. s3; pp. 321 - 329
• Main Authors: Reiman, Eric M., Langbaum, Jessica B.S., Fleisher, Adam S., Caselli, Richard J., Chen, Kewei, Ayutyanont, Napatkamon, Quiroz, Yakeel T., Kosik, Kenneth S., Lopera, Francisco, Tariot, Pierre N.
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2011
• Subjects: Alzheimer Disease - cerebrospinal fluid; Alzheimer Disease - genetics; Alzheimer Disease - pathology; Alzheimer Disease - prevention & control; Brain - pathology; Early Diagnosis; Humans; Magnetic Resonance Imaging; Brain imaging; surrogate markers; biomarkers; cerebral spinal fluid; apolipoprotein E; presenilin 1; presymptomatic Alzheimer's disease; early-onset Alzheimer's disease; clinical trials; late-onset Alzheimer's disease

There is an urgent need to find effective presymptomatic Alzheimer's disease (AD) treatments that reduce the risk of AD symptoms or prevent them completely. It currently takes too many healthy people, too much money and too many years to evaluate the range of promising presymptomatic treatments...