Hydrodynamic radius coincides with the slip plane position in the electrokinetic behavior of lysozyme

• Published in: Proteins, structure, function, and bioinformatics Vol. 86; no. 5; pp. 515 - 523
• Main Authors: Grisham, Daniel R., Nanda, Vikas
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2018
• Subjects: Albumen; Computer applications; Crystal structure; Diffusion layers; Drug development; Einstein equations; Electric double layer; Electrokinetics; Electrophoresis; Electrophoretic mobility; Electrostatic properties; Energy charge; Gouy–Chapman electric double layer; hydrodynamic radius; Lysozyme; Molecular structure; Protein structure; Proteins; Slip; slip plane position; Solvation; Stability analysis; Stokes–Einstein relation; Zeta potential; slip plane position; Gouy-Chapman electric double layer; zeta potential; Stokes-Einstein relation; hydrodynamic radius

The zeta potential (ζ) is the effective charge energy of a solvated protein, describing the magnitude of electrostatic interactions in solution. It is commonly used in the assessment of adsorption processes and dispersion stability. Predicting ζ from molecular structure would be useful to the struct...