Novel TREM2 splicing isoform that lacks the V‐set immunoglobulin domain is abundant in the human brain - Kiianitsa, Kostantin; Kurtz, Irina; Beeman, Neal; Matsushita, Mark; Chien, Wei‐Ming; Raskind, Wendy H.; Korvatska, Olena (Journal of leukocyte biology, 2021)
Keywords: Alternative RNA splicing; Alternative Splicing - physiology; Brain - metabolism; CD33; Humans; Immunoglobulin Domains; Interferon type I response; Membrane Glycoproteins - genetics; Membrane Glycoproteins - metabolism; Microglia - metabolism; Phagocytosis - genetics; Protein Isoforms - genetics; Protein Isoforms - metabolism; receptor shedding; Receptors, Immunologic - genetics; Receptors, Immunologic - metabolism; TREM2; Alternative RNA splicing; TREM2; receptor shedding; Interferon type I response; CD33