G protein‐coupled oestrogen receptor promotes cell growth of non‐small cell lung cancer cells via YAP1/QKI/circNOTCH1/m6A methylated NOTCH1 signalling

• Published in: Journal of cellular and molecular medicine Vol. 25; no. 1; pp. 284 - 296
• Main Authors: Shen, Yi, Li, Chong, Zhou, Lin, Huang, Jian‐An
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.01.2021; John Wiley and Sons Inc
• Subjects: Antibodies; Biomarkers; Breast cancer; Cell growth; circular RNA; Gene expression; Gene regulation; GPER; Lung cancer; N6-methyladenosine; Neoplasia; Non-small cell lung carcinoma; NOTCH1; Notch1 protein; NSCLC; Original; Phosphorylation; Plasmids; Proteins; Signal transduction; Small cell lung carcinoma; Transcription; Tumorigenesis; Tumors; Yes-associated protein; NOTCH1; NSCLC; circular RNA; GPER

Results from various studies reveal that the role of G protein‐coupled oestrogen receptor (GPER) is cancer‐context dependent, and the function of GPER in non–small‐cell lung cancer (NSCLC) is still unclear. The present study demonstrated that neoplasm lung tissues expressed higher level of GPER comp...