LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway - Zhong, Yu; Wu, Shun; Yang, Yan; Li, Gui‐qing; Meng, Li; Zheng, Quan‐you; Li, You; Xu, Gui‐lian; Zhang, Ke‐qin; Peng, Kan‐fu (Journal of cellular and molecular medicine, 2020)
Keywords: acute kidney injury; Acute Kidney Injury - metabolism; Acute Kidney Injury - pathology; Animals; Apoptosis; Cell injury; Cell Line; Down-Regulation; Fc receptors; Gene expression; Humans; Immunoregulation; Inflammation; Inflammation - pathology; Inflammation Mediators - metabolism; Kidneys; Laboratory animals; LIGHT; Lipopolysaccharides; Metastases; Mice, Knockout; Models, Biological; Morbidity; MyD88 protein; Myeloid Differentiation Factor 88 - metabolism; NF-kappa B - metabolism; NF‐κB; Original; Pathophysiology; Proteins; Reagents; Renal function; Sepsis; Sepsis - metabolism; Signal Transduction; Survival Analysis; TLR4; TLR4 protein; Toll-Like Receptor 4 - metabolism; Toll-like receptors; Tumor necrosis factor; Tumor Necrosis Factor Ligand Superfamily Member 14 - deficiency; Tumor Necrosis Factor Ligand Superfamily Member 14 - metabolism; Tumors; Beijing China; United States--US; China; Japan; NF-κB; acute kidney injury; TLR4; sepsis; LIGHT