Acetyltransferase p300 regulates atrial fibroblast senescence and age‐related atrial fibrosis through p53/Smad3 axis - Gao, Xiao‐Yan; Lai, Ying‐Yu; Luo, Xue‐Shan; Peng, De‐Wei; Li, Qiao‐Qiao; Zhou, Hui‐Shan; Xue, Yu‐Mei; Guo, Hui‐Ming; Zhao, Jun‐Fei; Yang, Hui; Kuang, Su‐Juan; Wang, Zhao‐Yu; et al. (Aging cell, 2023)
Keywords: Acetyltransferase; Acetyltransferases - metabolism; Age; Aged; Aging; Animals; atrial fibrillation; Atrial Fibrillation - metabolism; Atrial Fibrillation - pathology; Cardiac arrhythmia; Cardiomyopathy; Cardiovascular system; Cell cycle; Cellular Senescence - physiology; Collagen; Correlation analysis; Curcumin; Datasets; Diabetes; Fibroblasts; Fibroblasts - metabolism; Fibrosis; Genes; Geriatrics; GTP-binding protein; Heart attacks; Humans; Immunofluorescence; Immunoprecipitation; Mice; Overexpression; p300; p53; p53 Protein; Senescence; Smad3; Smad3 protein; Smad3 Protein - metabolism; Tumor Suppressor Protein p53 - metabolism; p300; senescence; Smad3; atrial fibrillation; fibrosis; p53