Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults - Chou, Chih‐Hung; Mohanty, Subhasis; Kang, Heather A.; Kong, Lingjia; Avila‐Pacheco, Julian; Joshi, Samit R.; Ueda, Ikuyo; Devine, Lesley; Raddassi, Khadir; Pierce, Kerry; Jeanfavre, Sarah; Bullock, Kevin; et al. (Aging cell, 2022)
Keywords: Age; Age groups; Aged; Amino acids; Antibiotics; Antibodies, Viral; Antibody response; Antigens; Combined vaccines; Esters; Fatty acids; Gender; Gene expression; Health care; Humans; Immune response; Immunomodulation; Inflammation; Influenza; Influenza Vaccines; Influenza, Human - genetics; Influenza, Human - prevention & control; Longitudinal studies; Metabolic response; Metabolism; Metabolites; Metabolomics; Morbidity; Older people; Pandemics; Plasma; Polyunsaturated fatty acids; Principal components analysis; Prostaglandins; systems biology; systems vaccinology; Transcriptome - genetics; Transcriptomics; Tryptophan; Vaccination; vaccine; Vaccines; Viruses; influenza; systems biology; vaccine; immune response; metabolomics; transcriptomics; systems vaccinology