Aberrations in Incentive Learning and Responding to Heroin in Male Rats After Adolescent or Adult Chronic Binge‐Like Alcohol Exposure

• Published in: Alcoholism, clinical and experimental research Vol. 44; no. 6; pp. 1214 - 1223
• Main Authors: Galaj, Ewa, Barrera, Eddy, Morris, Debra, Ma, Yao‐Ying, Ranaldi, Robert
• Format: Journal Article
• Language: English
• Published: England 01.06.2020
• Subjects: Alcohol; Animals; Behavior, Animal - physiology; Binge Drinking - physiopathology; Central Nervous System Depressants - pharmacology; Choice Behavior - drug effects; Chronic Intermittent Ethanol Exposure; Conditioned Approach; Conditioned Reinforcement; Conditioned Reward; Ethanol - pharmacology; Heroin - pharmacology; Heroin Sensitization; Incentive Learning; Learning - drug effects; Learning - physiology; Locomotion - drug effects; Male; Motivation; Narcotics - pharmacology; Rats; Reward; Conditioned Reward; Chronic Intermittent Ethanol Exposure; Conditioned Approach; Alcohol; Heroin Sensitization; Incentive Learning; Conditioned Reinforcement

Background and Purpose Binge drinking is a serious problem among adolescents and young adults despite its adverse consequences on the brain and behavior. One area that remains poorly understood concerns the impact of chronic intermittent ethanol (CIE) exposure on incentive learning. Methods Here, we...