Sulcal Depth-Position Profile Is a Genetically Mediated Neuroscientific Trait: Description and Characterization in the Central Sulcus

• Published in: The Journal of neuroscience Vol. 33; no. 39; pp. 15618 - 15625
• Main Authors: McKay, D. Reese, Kochunov, Peter, Cykowski, Matthew D., Kent, Jack W., Laird, Angela R., Lancaster, Jack L., Blangero, John, Glahn, David C., Fox, Peter T.
• Format: Journal Article
• Language: English
• Published: United States Society for Neuroscience 25.09.2013
• Subjects: Adult; Aged; Aged, 80 and over; Cerebral Cortex - anatomy & histology; Cerebral Cortex - physiology; Female; Fingers - innervation; Fingers - physiology; Functional Laterality; Gene-Environment Interaction; Genetic Pleiotropy; Humans; Male; Mexican Americans - genetics; Middle Aged; Mouth - innervation; Mouth - physiology; Movement; Pedigree; Quantitative Trait, Heritable

Genetic and environmental influences on brain morphology were assessed in an extended-pedigree design by extracting depth-position profiles (DPP) of the central sulcus (CS). T1-weighted magnetic resonance images were used to measure CS length and depth in 467 human subjects from 35 extended families...