Double-Blind, Bilateral Pain Comparison with Simultaneous Injection of 2% Lidocaine versus Buffered 2% Lidocaine for Periocular Anesthesia

• Published in: Ophthalmology (Rochester, Minn.) Vol. 119; no. 10; pp. 2048 - 2052
• Main Authors: Welch, Mark N., DO, Czyz, Craig N., DO, FACOS, Kalwerisky, Kevin, MD, Holck, David E.E., MD, FACS, Mihora, Lisa D., MD
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.10.2012; Elsevier
• Subjects: Adult; Aged; Aged, 80 and over; Anesthesia, Local - methods; Anesthetics, Local - administration & dosage; Biological and medical sciences; Blepharoplasty; Buffers; Double-Blind Method; Epinephrine - administration & dosage; Eye Pain - diagnosis; Female; Humans; Hydrogen-Ion Concentration; Injections, Intraocular; Lidocaine - administration & dosage; Male; Medical sciences; Middle Aged; Miscellaneous; Ophthalmology; Orbit - drug effects; Pain Measurement; Prospective Studies; Rhytidoplasty; Sodium Bicarbonate; Blind; Bilateral; Anticonvulsant; Injection; Antiarrhythmic agent; Periphery; Local anesthetic; Eye; Pain; Periocular; Anesthesia; Organic amide; Ophthalmology; Lidocaine; Comparative study

Purpose Determine if raising the pH of 2% lidocaine with epinephrine 1:100 000 to a physiologic level decreases pain perception during periocular, subcutaneous anesthesia. Design Double-blind, prospective, randomized study. Simultaneous unilateral injections of buffered and unbuffered lidocaine solu...