Tetrathiomolybdate, a copper chelator inhibited imiquimod-induced skin inflammation in mice - Hsu, Peng-Yang; Yen, Hsu-Heng; Yang, Tao-Hsiang; Su, Che-Chun (Journal of dermatological science, 2018)
Keywords: Animals; Anti-Inflammatory Agents - pharmacology; Chelating Agents - pharmacology; Copper; Copper - metabolism; Cytokines - metabolism; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases - metabolism; Imiquimod; Inflammation Mediators - metabolism; Keratinocytes - drug effects; Keratinocytes - immunology; Keratinocytes - metabolism; Male; Mice, Inbred C57BL; Molybdenum - pharmacology; Phosphorylation; Psoriasis; Psoriasis - chemically induced; Psoriasis - immunology; Psoriasis - metabolism; Psoriasis - prevention & control; Signal Transduction - drug effects; Skin - drug effects; Skin - immunology; Skin - metabolism; Skin - pathology; Spleen - drug effects; Spleen - immunology; Spleen - metabolism; STAT3 Transcription Factor - metabolism; Tetrathiomolybdate; Tetrathiomolybdate; Psoriasis; Copper; Imiquimod