miR-497-5p inhibits gastric cancer cell proliferation and growth through targeting PDK3

• Published in: Bioscience reports Vol. 39; no. 9
• Main Authors: Feng, Lan, Cheng, Kai, Zang, Rongjia, Wang, Qingdong, Wang, Jianjie
• Format: Journal Article
• Language: English
• Published: England Portland Press Ltd 30.09.2019
• Subjects: DNA synthesis; PDK3; apoptosis; gastric cancer; cell cycle; miR-497-5p

MicroRNA plays an important role in gastric cancer (GC) development, while the function of miR-497-5p in this disease remains unknown. In the present study, we demonstrated miR-497-5p as a tumor suppressive microRNA in GC. miR-497-5p was down-regulated in GC tissues and its expression was associated...