ATG5 promotes eosinopoiesis but inhibits eosinophil effector functions

• Published in: Blood Vol. 137; no. 21; pp. 2958 - 2969
• Main Authors: Germic, Nina, Hosseini, Aref, Stojkov, Darko, Oberson, Kevin, Claus, Meike, Benarafa, Charaf, Calzavarini, Sara, Angelillo-Scherrer, Anne, Arnold, Isabelle C., Müller, Anne, Riether, Carsten, Yousefi, Shida, Simon, Hans-Uwe
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 27.05.2021; American Society of Hematology
• Subjects: Phagocytes, Granulocytes, and Myelopoiesis

Eosinophils are white blood cells that contribute to the regulation of immunity and are involved in the pathogenesis of numerous inflammatory diseases. In contrast to other cells of the immune system, no information is available regarding the role of autophagy in eosinophil differentiation and funct...