The Effects of Combined Versus Selective Adrenergic Blockade on Left Ventricular and Systemic Hemodynamics, Myocardial Substrate Preference, and Regional Perfusion in Conscious Dogs With Dilated Cardiomyopathy

• Published in: Journal of the American College of Cardiology Vol. 47; no. 9; pp. 1871 - 1881
• Main Authors: Nikolaidis, Lazaros A., Poornima, Indu, Parikh, Pratik, Magovern, Megan, Shen, You-Tang, Shannon, Richard P.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 02.05.2006; Elsevier Science; Elsevier Limited
• Subjects: Adrenergic Antagonists - therapeutic use; Adrenergic beta-Agonists - pharmacology; Animals; Biological and medical sciences; Carbazoles - therapeutic use; Cardiology; Cardiology. Vascular system; Cardiomyopathy; Cardiomyopathy, Dilated - drug therapy; Cardiomyopathy, Dilated - metabolism; Cardiomyopathy, Dilated - physiopathology; Dogs; Fatty acids; Heart; Heart rate; Heart Rate - drug effects; Hemodynamics - drug effects; Isoproterenol - pharmacology; Laboratory animals; Medical sciences; Metoprolol - analogs & derivatives; Metoprolol - therapeutic use; Mortality; Myocarditis. Cardiomyopathies; Myocardium - metabolism; Plasma; Propanolamines - therapeutic use; Regional Blood Flow - drug effects; Rodents; Ventricular Function, Left - drug effects; CR/XL; COMET; Mvo2; LV; cAMP; SVR; DCM; LVEDP; ANOVA; dP/dt; GTP/Iso; NEFA; NE; Regional perfusion; Fissipedia; Carnivora; Cardiovascular disease; Systemic; Myocardial disease; Phlebology; Left ventricle; Substrate; Vertebrata; Mammalia; Congestive hypertrophic cardiomyopathy; Preference; Heart disease; Animal; Circulatory system; Disseminated; Hemodynamics; Cardiology; Dog; Comparative study

The Effects of Combined Versus Selective Adrenergic Blockade on Left Ventricular and Systemic Hemodynamics, Myocardial Substrate Preference, and Regional Perfusion in Conscious Dogs With Dilated Cardiomyopathy Lazaros A. Nikolaidis, Indu Poornima, Pratik Parikh, Megan Magovern, You-Tang Shen, Richar...