Dissecting the low catalytic capability of flavin-dependent halogenases - Phintha, Aisaraphon; Prakinee, Kridsadakorn; Jaruwat, Aritsara; Lawan, Narin; Visitsatthawong, Surawit; Kantiwiriyawanitch, Chadaporn; Songsungthong, Warangkhana; Trisrivirat, Duangthip; Chenprakhon, Pirom; Mulholland, Adrian; van Pée, Karl-Heinz; Chitnumsub, Penchit; et al. (The Journal of biological chemistry, 2021)
Keywords: Catalysis; Crystallography, X-Ray; flavin monooxygenase; Flavin-Adenine Dinucleotide - metabolism; Flavins - metabolism; halogenase; Halogenation; Hydrogen Peroxide - metabolism; Kinetics; Models, Molecular; Oxidoreductases - metabolism; Protein Conformation; QM/MM calculations; stopped-flow; X-ray structures; halogenase; C1; Na2S2O4; flavin monooxygenase; PrnA; HOBr; QM/MM calculations; Thal; PyrH; HCOONa; X-ray structures; HPLC; FADH; HOI; DAD; MS; FAD; QM/MM; stopped-flow; HOX; NAD; HOCl; psFDH; DMSO-d6; kinetics