oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data

• Published in: Briefings in bioinformatics Vol. 22; no. 6
• Main Authors: Maeser, Danielle, Gruener, Robert F, Huang, Rong Stephanie
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 05.11.2021
• Subjects: Antineoplastic Agents - therapeutic use; Biomarkers, Tumor - metabolism; Cell Line, Tumor; Humans; Problem Solving Protocol; Software; biomarker identification; drug discovery; drug response prediction

Cell line drug screening datasets can be utilized for a range of different drug discovery applications from drug biomarker discovery to building translational models of drug response. Previously, we described three separate methodologies to (1) correct for general levels of drug sensitivity to enabl...