Categorizing Extrachromosomal Circular DNA as Biomarkers in Serum of Cancer

• Published in: Biomolecules (Basel, Switzerland) Vol. 14; no. 4; p. 488
• Main Authors: Deng, Enze, Fan, Xiaoying
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2024
• Subjects: biomarker; Biomarkers; Biomarkers, Tumor - blood; Biomarkers, Tumor - genetics; Biopsy; Cancer; Cancer therapies; Cell division; Chromosomes; Circular DNA; Diagnosis; DNA, Circular - blood; DNA, Circular - genetics; extrachromosomal circular DNA; Gene amplification; Genetic aspects; Genomes; Health aspects; Humans; Liquid Biopsy - methods; Microscopy; Neoplasms - blood; Neoplasms - diagnosis; Neoplasms - genetics; Prognosis; Roles; serum; Tumorigenesis; Tumors; China; cancer; biomarker; serum; extrachromosomal circular DNA

Extrachromosomal circular DNA (eccDNA), a double-stranded circular DNA molecule found in multiple organisms, has garnered an increasing amount of attention in recent years due to its close association with the initiation, malignant progression, and heterogeneous evolution of cancer. The presence of...