A functional magnetic resonance imaging study mapping the episodic memory encoding network in temporal lobe epilepsy

• Published in: Brain (London, England : 1878) Vol. 136; no. 6; pp. 1868 - 1888
• Main Authors: Sidhu, Meneka K., Stretton, Jason, Winston, Gavin P., Bonelli, Silvia, Centeno, Maria, Vollmar, Christian, Symms, Mark, Thompson, Pamela J., Koepp, Matthias J., Duncan, John S.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.06.2013
• Subjects: Adult; Amygdala; Biological and medical sciences; Brain Mapping - methods; Epilepsy, Temporal Lobe - pathology; Epilepsy, Temporal Lobe - physiopathology; Female; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Hippocampus - pathology; Hippocampus - physiology; Humans; Magnetic Resonance Imaging - methods; Male; Medical sciences; Memory, Episodic; Middle Aged; Nerve Net - pathology; Nerve Net - physiology; Nervous system (semeiology, syndromes); Neurology; Original; Prefrontal Cortex - pathology; Prefrontal Cortex - physiology; Sclerosis - pathology; Young Adult; Cartography; functional MRI; Nervous system diseases; Central nervous system disease; Complex partial epilepsy; Temporal lobe epilepsy; Nuclear magnetic resonance imaging; Episodic memory; Cerebral disorder; Functional imaging; episodic memory; temporal lobe epilepsy

Functional magnetic resonance imaging has demonstrated reorganization of memory encoding networks within the temporal lobe in temporal lobe epilepsy, but little is known of the extra-temporal networks in these patients. We investigated the temporal and extra-temporal reorganization of memory encodin...