Statins in Primary Prevention in People Over 80 Years

• Published in: The American journal of cardiology Vol. 187; pp. 62 - 73
• Main Authors: Marcellaud, Elodie, Jost, Jeremy, Tchalla, Achille, Magne, Julien, Aboyans, Victor
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.01.2023; Elsevier Limited
• Subjects: Age; Aged, 80 and over; Bias; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - drug therapy; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - prevention & control; Cause of Death; Cholesterol; Clinical trials; Diabetes; Effectiveness; Gastrointestinal diseases; Heart attacks; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Hypercholesterolemia; Life expectancy; Life span; Lipids; Literature reviews; Medical research; Medical Subject Headings-MeSH; Mortality; Patient safety; Primary Prevention; Risk levels; Side effects; Statins; Stroke; Transposition

In the much older population (≥80 years), the management of cardiovascular diseases requires specific research to avoid a plain transposition of medical practice from younger populations. Whether statins are useful in primary prevention in this population is not clear. The 3 intricate issues requiri...