A blood-based signature of cerebrospinal fluid Aβ1–42 status

• Published in: Scientific reports Vol. 9; no. 1; p. 4163
• Main Authors: Goudey, Benjamin, Fung, Bowen J., Schieber, Christine, Faux, Noel G.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 11.03.2019; Nature Publishing Group
• Subjects: 692/53/2421; 692/53/2422; 692/53/2423; 692/617/375/132/1283; Alzheimer's disease; Apolipoprotein E; Artificial intelligence; Blood; Cerebrospinal fluid; Cognitive ability; Dementia disorders; Emission measurements; Eotaxin; Health risks; Humanities and Social Sciences; Learning algorithms; multidisciplinary; Positron emission tomography; Science; Science (multidisciplinary)

It is increasingly recognized that Alzheimer’s disease (AD) exists before dementia is present and that shifts in amyloid beta occur long before clinical symptoms can be detected. Early detection of these molecular changes is a key aspect for the success of interventions aimed at slowing down rates o...