ACSL1 Regulates TNFα-Induced GM-CSF Production by Breast Cancer MDA-MB-231 Cells

• Published in: Biomolecules (Basel, Switzerland) Vol. 9; no. 10; p. 555
• Main Authors: Thomas, Reeby, Al-Rashed, Fatema, Akhter, Nadeem, Al-Mulla, Fahd, Ahmad, Rasheed
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 01.10.2019; MDPI AG
• Subjects: acsl1; gm-csf; mda-mb-231; tnfα; TNFα; ACSL1; GM-CSF; MDA-MB-231

Overexpression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in different types of cancer is associated with tumor growth and progression. Tumor necrosis factor-α (TNFα) is involved in the induction of GM-CSF in different cells; however, the underlying molecular mechanism in this prod...