Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1 - Peng, Shiming; Xiao, Wen; Ju, Dapeng; Sun, Baofa; Hou, Nannan; Liu, Qianlan; Wang, Yanli; Zhao, Haijiao; Gao, Chunchun; Zhang, Song; Cao, Ran; Li, Pengfei; et al. (Science translational medicine, 2019)
Keywords: Animals; Blood Glucose - drug effects; Body Weight - drug effects; Body Weight - physiology; Catechol O-Methyltransferase - genetics; Catechol O-Methyltransferase - metabolism; Catechols - pharmacology; Enzyme Inhibitors - pharmacology; Forkhead Box Protein O1 - genetics; Forkhead Box Protein O1 - metabolism; Humans; Mice; Nitriles - pharmacology; RNA, Messenger - genetics; RNA, Messenger - metabolism; Thermogenesis - drug effects; Thermogenesis - genetics; Thermogenesis - physiology