Insight facilitation with add-on tDCS in schizophrenia
Abstract Impaired insight in schizophrenia patients has been linked with prefrontal deficits. In this open-label study, we examined for potential insight facilitation effects of add-on tDCS (with anodal stimulation of left DLPFC and cathodal stimulation over left temporo-parietal junction) in schizo...
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Published in | Schizophrenia research Vol. 156; no. 1; pp. 63 - 65 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier B.V
01.06.2014
Elsevier |
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Abstract | Abstract Impaired insight in schizophrenia patients has been linked with prefrontal deficits. In this open-label study, we examined for potential insight facilitation effects of add-on tDCS (with anodal stimulation of left DLPFC and cathodal stimulation over left temporo-parietal junction) in schizophrenia patients (N = 21) with persistent auditory hallucinations despite adequate antipsychotic treatment. Following tDCS, there was a significant improvement in insight with concurrent significant reduction in auditory hallucination severity. Improvement in insight correlated significantly with improvement in severity of auditory hallucinations. These findings suggest improvement of insight with add-on tDCS in schizophrenia with persistent auditory hallucinations. |
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AbstractList | Impaired insight in schizophrenia patients has been linked with prefrontal deficits. In this open-label study, we examined for potential insight facilitation effects of add-on tDCS (with anodal stimulation of left DLPFC and cathodal stimulation over left temporo-parietal junction) in schizophrenia patients (N=21) with persistent auditory hallucinations despite adequate antipsychotic treatment. Following tDCS, there was a significant improvement in insight with concurrent significant reduction in auditory hallucination severity. Improvement in insight correlated significantly with improvement in severity of auditory hallucinations. These findings suggest improvement of insight with add-on tDCS in schizophrenia with persistent auditory hallucinations. Abstract Impaired insight in schizophrenia patients has been linked with prefrontal deficits. In this open-label study, we examined for potential insight facilitation effects of add-on tDCS (with anodal stimulation of left DLPFC and cathodal stimulation over left temporo-parietal junction) in schizophrenia patients (N = 21) with persistent auditory hallucinations despite adequate antipsychotic treatment. Following tDCS, there was a significant improvement in insight with concurrent significant reduction in auditory hallucination severity. Improvement in insight correlated significantly with improvement in severity of auditory hallucinations. These findings suggest improvement of insight with add-on tDCS in schizophrenia with persistent auditory hallucinations. |
Author | Shivakumar, Venkataram Chhabra, Harleen Bose, Anushree Agarwal, Sri Mahavir Kalmady, Sunil V Venkatasubramanian, Ganesan Narayanaswamy, Janardhanan C Subramaniam, Aditi Nawani, Hema |
Author_xml | – sequence: 1 fullname: Bose, Anushree – sequence: 2 fullname: Shivakumar, Venkataram – sequence: 3 fullname: Narayanaswamy, Janardhanan C – sequence: 4 fullname: Nawani, Hema – sequence: 5 fullname: Subramaniam, Aditi – sequence: 6 fullname: Agarwal, Sri Mahavir – sequence: 7 fullname: Chhabra, Harleen – sequence: 8 fullname: Kalmady, Sunil V – sequence: 9 fullname: Venkatasubramanian, Ganesan |
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Keywords | DLPFC Scale to Assess Unawareness of Mental Disorder auditory hallucination score Auditory hallucinations Schizophrenia AHS dorsolateral prefrontal cortex TPJ transcranial Direct Current Stimulation Schedule for Assessment of Insight tDCS Insight SAI SUMD temporo-parietal junction Psychosis Facilitation Human Treatment efficiency Auditory hallucination Transcranial electrical stimulation |
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Snippet | Abstract Impaired insight in schizophrenia patients has been linked with prefrontal deficits. In this open-label study, we examined for potential insight... Impaired insight in schizophrenia patients has been linked with prefrontal deficits. In this open-label study, we examined for potential insight facilitation... |
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SubjectTerms | Adult Antipsychotic Agents - therapeutic use Auditory hallucinations Biological and medical sciences Electric Stimulation Therapy - methods Electric Stimulation Therapy - psychology Female Hallucinations - etiology Hallucinations - therapy Humans Insight Male Medical sciences Middle Aged Miscellaneous Psychiatric Status Rating Scales Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Schizophrenia Schizophrenia - complications Schizophrenia - therapy Schizophrenic Psychology tDCS Treatments Young Adult |
Title | Insight facilitation with add-on tDCS in schizophrenia |
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