Threat of Punishment Motivates Memory Encoding via Amygdala, Not Midbrain, Interactions with the Medial Temporal Lobe

• Published in: The Journal of neuroscience Vol. 32; no. 26; pp. 8969 - 8976
• Main Authors: Murty, V. P., LaBar, K. S., Adcock, R. A.
• Format: Journal Article
• Language: English
• Published: United States Society for Neuroscience 27.06.2012
• Subjects: Adolescent; Adult; Amygdala - blood supply; Amygdala - physiology; Efferent Pathways - blood supply; Efferent Pathways - physiology; Electroshock - adverse effects; Emotions - physiology; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Memory - physiology; Mesencephalon - blood supply; Mesencephalon - physiology; Motivation - physiology; Oxygen - blood; Punishment - psychology; Temporal Lobe - blood supply; Temporal Lobe - physiology; Young Adult

Neural circuits associated with motivated declarative encoding and active threat avoidance have both been described, but the relative contribution of these systems to punishment-motivated encoding remains unknown. The current study used functional magnetic resonance imaging in humans to examine mech...