Non-conventional hemostatic risk factors for coronary heart disease in individuals with spinal cord injury

• Published in: Spinal cord Vol. 49; no. 8; pp. 858 - 866
• Main Authors: Khan, B, Bauman, W A, Sinha, A K, Kahn, N N
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.08.2011; Nature Publishing Group
• Subjects: 631/250/2152/2153/1291; 631/378/1687/1825; 692/499; 692/699/75/593/15; Anatomy; Arteriosclerosis; Atherogenesis; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Blood Platelets - metabolism; Cerebrospinal fluid. Meninges. Spinal cord; Coronary Disease - epidemiology; Coronary Disease - etiology; Coronary heart disease; Diabetes mellitus; Epoprostenol - metabolism; Etiology; Hemostatics - metabolism; Human Physiology; Humans; Hyperactivity; Hyperlipidemia; Immunoglobulin G; Injuries of the nervous system and the skull. Diseases due to physical agents; Insulin; Insulin receptors; Medical sciences; Nervous system (semeiology, syndromes); Neurochemistry; Neurology; Neuropsychology; Neurosciences; Nitric Oxide - metabolism; Platelet aggregation; Platelet-derived growth factor; Platelet-Derived Growth Factor - metabolism; prostacyclin PGI2; PubMed - statistics & numerical data; Receptor mechanisms; review; Reviews; Risk Factors; Spinal Cord Injuries - epidemiology; Spinal cord injury; Thrombin; Thrombin - metabolism; Thrombosis; Time Factors; Traumas. Diseases due to physical agents; Tritium - metabolism; coronary heart disease; antibody; insulin; prostacyclin; platelets; Pancreatic hormone; Nervous system diseases; Vertebral canal; Hemostatic; Prostaglandin I2; Cardiovascular disease; Coronary heart disease; Insulin; Platelet; Spinal cord trauma; Central nervous system disease; Risk factor; Spinal cord disease

Study design: Review. Objectives: In subjects with spinal cord injury (SCI), there is strong evidence for platelet hyperactivity, which may stimulate atherosclerosis and coronary heart disease (CHD). The literature was reviewed. Background: Individuals with SCI develop premature CHD. In addition to...