Mapping a new suggestive gene locus for autosomal dominant nephrolithiasis to chromosome 9q33.2–q34.2 by total genome search for linkage

• Published in: Nephrology, dialysis, transplantation Vol. 20; no. 5; pp. 909 - 914
• Main Authors: Wolf, Matthias T. F., Zalewski, Isabella, Martin, Félix Claverie, Ruf, Rainer, Müller, Dominik, Hennies, Hans C., Schwarz, Stella, Panther, Franziska, Attanasio, Massimo, Acosta, Hilaria G., Imm, Anita, Lucke, Barbara, Utsch, Boris, Otto, Edgar, Nurnberg, Peter, Nieto, Victor Garcia, Hildebrandt, Friedhelm
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.05.2005; Oxford Publishing Limited (England)
• Subjects: Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Chromosome Mapping; Chromosomes, Human, Pair 9; Emergency and intensive care: renal failure. Dialysis management; Female; Genetic Linkage; Genome; haplotype analysis; Humans; Intensive care medicine; Kidney Calculi - genetics; Kidneys; Lod Score; Male; Malformations of the urinary system; Medical sciences; Microsatellite Repeats; Middle Aged; nephrolithiasis; Nephrology. Urinary tract diseases; recombination; Tumors of the urinary system; Kidney disease; Cartography; Extrarenal dialysis; haplotype analysis; Urinary system disease; recombination; Hemodialysis; Renal failure; Genetic linkage; nephrolithiasis; Locus

Background. Nephrolithiasis is a complex, multifactorial disease resulting from genetic and environmental interaction. The pathogenesis of nephrolithiasis is far from being understood. So far, no gene locus for autosomal dominant nephrolithiasis only has been described. We here identified a new sugg...