An Automatic Tool for Quantification of Nerve Fibers in Corneal Confocal Microscopy Images - Chen, Xin; Graham, Jim; Dabbah, Mohammad A.; Petropoulos, Ioannis N.; Tavakoli, Mitra; Malik, Rayaz A. (IEEE transactions on biomedical engineering, 2017)
Keywords: Algorithms; Automation; Biomarkers; Biomedical measurement; Clinical trials; Computer aided diagnosis; Confocal microscopy; Cornea; Cornea - diagnostic imaging; Cornea - innervation; Cornea - pathology; corneal confocal microscopy (CCM); Correlation analysis; Diabetes; Diabetes mellitus; Diabetes mellitus (insulin dependent); Diabetic Neuropathies - diagnostic imaging; Diabetic Neuropathies - pathology; diabetic sensorimotor polyneuropathy (DSPN); Discrete wavelet transforms; Error detection; Feature extraction; Humans; image analysis; Image detection; Image Interpretation, Computer-Assisted - methods; Machine Learning; Medical imaging; Medical research; Microscopy; Microscopy, Confocal - methods; Morphology; Nerve Fibers - pathology; nerve-fiber quantification; Nerves; Patients; Pattern Recognition, Automated - methods; Peripheral neuropathy; Polyneuropathy; Reproducibility of Results; Sensitivity; Sensitivity and Specificity; Sensorimotor system; Software development tools; Training