Strong density-dependent competition and acquired immunity constrain parasite establishment: Implications for parasite aggregation

• Published in: International journal for parasitology Vol. 41; no. 5; pp. 505 - 511
• Main Authors: Luong, Lien T., Vigliotti, Beth A., Hudson, Peter J.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.04.2011; Elsevier
• Subjects: Adaptive Immunity; Aggregation; Animals; Biological and medical sciences; Challenge infection; Complex life cycle; Density dependence; Disease Models, Animal; Fundamental and applied biological sciences. Psychology; Gryllidae - parasitology; Host-Parasite Interactions; hosts; Humans; immune response; immunoglobulin G; Insect Vectors - parasitology; Life cycle. Host-agent relationship. Pathogenesis; Male; Mammalia; Mice; Nematoda - growth & development; Nematoda - immunology; Nematoda - physiology; Nematode Infections - immunology; Nematode Infections - parasitology; parasites; Peromyscus; Peromyscus leucopus; Protozoa; Trophic transmission; Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution; Aggregation; Density dependence; Trophic transmission; Challenge infection; Complex life cycle; Peromyscus; Competition; Acquired immunity; Rodentia; Transmission; Parasite; Trophic relation; Strong; Infection; Life cycle; Vertebrata; Mammalia

[Display omitted] ► Strong density-dependence generates exceptional parasite distribution. ► Hosts develop acquired immunity against parasites with a complex life cycle. ► The ability to mount immune memory is also density-dependent. ► Worm size and immune IgG levels also support this conclusion. Th...