Epidemiological and clinical features of mpox during the clade Ib outbreak in South Kivu, Democratic Republic of the Congo: a prospective cohort study

• Published in: The Lancet (British edition) Vol. 405; no. 10478; pp. 547 - 559
• Main Authors: Brosius, Isabel, Vakaniaki, Emmanuel Hasivirwe, Mukari, Guy, Munganga, Papy, Tshomba, Jean Claude, De Vos, Elise, Bangwen, Eugene, Mujula, Yves, Tsoumanis, Achilleas, Van Dijck, Christophe, Alengo, Aimé, Mutimbwa-Mambo, Léandre, Kumbana, Franklin Mweshi, Munga, Jenestin Babingwa, Mambo, Divin Mazambi, Zangilwa, James Wakilongo, Kitwanda, Steeven Bilembo, Houben, Sarah, Hoff, Nicole A, Makangara-Cigolo, Jean-Claude, Kinganda-Lusamaki, Eddy, Peeters, Martine, Rimoin, Anne W, Kindrachuk, Jason, Low, Nicola, Katoto, Patrick D M C, Malembaka, Espoir Bwenge, Amuasi, John H, Tshiani-Mbaya, Olivier, Kambaji, Dally Muamba, Kojan, Richard, Kacita, Cris, Mukadi-Bamuleka, Daniel, Ahuka-Mundeke, Steve, Vercauteren, Koen, Wawina-Bokalanga, Tony, Muyembe-Tamfum, Jean-Jacques, Nundu, Sabin Sabiti, Liesenborghs, Laurens, Mbala-Kingebeni, Placide
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.02.2025; Elsevier Limited
• Subjects: Adolescent; Adult; Adults; Age composition; At risk populations; Case reports; Child; Child, Preschool; Children; Clinical trials; Cohort analysis; Comorbidity; Complications; Consent; Democratic Republic of the Congo - epidemiology; Developing countries; Disease Outbreaks; Disease transmission; Epidemics; Epidemiology; Fatalities; Female; Health promotion; Hospitals; Humans; Infant; Infections; LDCs; Lesions; Lymphadenopathy; Male; Medical diagnosis; Middle Aged; Monkeypox virus - classification; Monkeypox virus - genetics; Monkeypox virus - isolation & purification; Mortality; Mpox; Mpox, Monkeypox - diagnosis; Mpox, Monkeypox - epidemiology; Mpox, Monkeypox - transmission; Mpox, Monkeypox - virology; Observational studies; Outbreaks; Patients; Pregnancy; Prospective Studies; Public health; Sexual partners; Sexually transmitted diseases; Skin diseases; Skin lesions; STD; Urogenital system; Viral diseases; Women; Womens health; Young Adult; Zoonoses; Democratic Republic of the Congo; Congo-Democratic Republic of Congo; United States > US; Africa

Clade Ib, a new strain of clade I monkeypox virus, emerged in eastern DR Congo, sparking an international outbreak. Comprehensive studies are needed to assess its transmission dynamics and clinical presentation. We did a prospective observational cohort study at Kamituga General Hospital in South Ki...