Poly (butylene adipate-co-terephthalate)/Sodium alginate blends have superior characteristics and can be used to fabricate vascular stents

Abstract To investigate the physical properties and in vitro biocompatibility of Poly (butylene adipate-co-terephthalate) and Sodium alginate (PBAT/SA) melt blending, as well as feasibility of using PBAT/SA blending materials to fabricate vascular stents through 3D printing technology. PBAT/SA compo...

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Published inMaterials research express Vol. 9; no. 5; pp. 55401 - 55410
Main Authors Qiu, ShuiWei, Xia, YingHui, Sun, JiangDong, Wang, ShanShan, Xing, QuanSheng
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.05.2022
Subjects
3-D printers
3D printing
Apoptosis
Biocompatibility
biodegradable stents
Contact angle
degradable materials
Feasibility studies
Hydrophilicity
Melt blending
PBAT
Physical properties
Sodium alginate
Stents
Technology utilization
Terephthalate
Thermodynamic properties
Three dimensional printing
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Abstract Abstract To investigate the physical properties and in vitro biocompatibility of Poly (butylene adipate-co-terephthalate) and Sodium alginate (PBAT/SA) melt blending, as well as feasibility of using PBAT/SA blending materials to fabricate vascular stents through 3D printing technology. PBAT/SA composites were prepared by melt blending, and then related physical properties were assessed through FTIR, SEM, DSC, and water contact angle tests. The effects of the PBAT/SA blend on cell morphology, ROS, apoptosis, and cell proliferation were analyzed in vitro . In addition, we employed a 4-axis 3D printer to evaluate the feasibility of using PBAT/SA blend materials to fabricate vascular stents. We successfully prepared PBAT/SA melt blended materials. FTIR and SEM analyses demonstrated that PBAT and SA were compatible, while DSC data confirmed that the addition of SA improved the thermal properties of PBAT. Besides, water contact angle analysis showed that SA improved the hydrophilicity of PBAT. In addition, we successfully fabricated PBAT/SA vascular stent using 4-axis 3D printing technology. Our data showed that PBAT and SA are compatible, and the addition of SA enhances the thermal properties and hydrophilicity of PBAT. In addition, PBAT/SA blend materials can be fabricated into vascular stents using 4-axis 3D printing technology.
AbstractList To investigate the physical properties and in vitro biocompatibility of Poly (butylene adipate-co-terephthalate) and Sodium alginate (PBAT/SA) melt blending, as well as feasibility of using PBAT/SA blending materials to fabricate vascular stents through 3D printing technology. PBAT/SA composites were prepared by melt blending, and then related physical properties were assessed through FTIR, SEM, DSC, and water contact angle tests. The effects of the PBAT/SA blend on cell morphology, ROS, apoptosis, and cell proliferation were analyzed in vitro. In addition, we employed a 4-axis 3D printer to evaluate the feasibility of using PBAT/SA blend materials to fabricate vascular stents. We successfully prepared PBAT/SA melt blended materials. FTIR and SEM analyses demonstrated that PBAT and SA were compatible, while DSC data confirmed that the addition of SA improved the thermal properties of PBAT. Besides, water contact angle analysis showed that SA improved the hydrophilicity of PBAT. In addition, we successfully fabricated PBAT/SA vascular stent using 4-axis 3D printing technology. Our data showed that PBAT and SA are compatible, and the addition of SA enhances the thermal properties and hydrophilicity of PBAT. In addition, PBAT/SA blend materials can be fabricated into vascular stents using 4-axis 3D printing technology.
Abstract To investigate the physical properties and in vitro biocompatibility of Poly (butylene adipate-co-terephthalate) and Sodium alginate (PBAT/SA) melt blending, as well as feasibility of using PBAT/SA blending materials to fabricate vascular stents through 3D printing technology. PBAT/SA composites were prepared by melt blending, and then related physical properties were assessed through FTIR, SEM, DSC, and water contact angle tests. The effects of the PBAT/SA blend on cell morphology, ROS, apoptosis, and cell proliferation were analyzed in vitro . In addition, we employed a 4-axis 3D printer to evaluate the feasibility of using PBAT/SA blend materials to fabricate vascular stents. We successfully prepared PBAT/SA melt blended materials. FTIR and SEM analyses demonstrated that PBAT and SA were compatible, while DSC data confirmed that the addition of SA improved the thermal properties of PBAT. Besides, water contact angle analysis showed that SA improved the hydrophilicity of PBAT. In addition, we successfully fabricated PBAT/SA vascular stent using 4-axis 3D printing technology. Our data showed that PBAT and SA are compatible, and the addition of SA enhances the thermal properties and hydrophilicity of PBAT. In addition, PBAT/SA blend materials can be fabricated into vascular stents using 4-axis 3D printing technology.
Author Sun, JiangDong
Qiu, ShuiWei
Wang, ShanShan
Xing, QuanSheng
Xia, YingHui
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crossref_primary_10_1016_j_marpolbul_2024_116261
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Snippet Abstract To investigate the physical properties and in vitro biocompatibility of Poly (butylene adipate-co-terephthalate) and Sodium alginate (PBAT/SA) melt...
To investigate the physical properties and in vitro biocompatibility of Poly (butylene adipate-co-terephthalate) and Sodium alginate (PBAT/SA) melt blending,...
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SubjectTerms 3-D printers
3D printing
Apoptosis
Biocompatibility
biodegradable stents
Contact angle
degradable materials
Feasibility studies
Hydrophilicity
Melt blending
PBAT
Physical properties
Sodium alginate
Stents
Technology utilization
Terephthalate
Thermodynamic properties
Three dimensional printing
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Title Poly (butylene adipate-co-terephthalate)/Sodium alginate blends have superior characteristics and can be used to fabricate vascular stents
URI https://iopscience.iop.org/article/10.1088/2053-1591/ac6a4c
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