Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family

• Published in: FEBS letters Vol. 261; no. 2; pp. 397 - 401
• Main Authors: Schoofs, Liliane, Holman, G.Mark, Hayes, Timothy K., Nachman, Ronald J., De Loof, Arnold
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 26.02.1990; Elsevier
• Subjects: Acrididae; Amino Acid Sequence; Amino Acids - analysis; Aminoacids, peptides. Hormones. Neuropeptides; Analytical, structural and metabolic biochemistry; Animals; Biological and medical sciences; Biological Assay; Brain Chemistry; Chromatography, High Pressure Liquid; Cockroaches; Fundamental and applied biological sciences. Psychology; Grasshoppers - analysis; Homology; Insect Hormones - isolation & purification; Insect Hormones - pharmacology; Insect neuropeptide; Insect Proteins; Locusta migratoria; Locustatachykinin; locustatachykinin II; Molecular Sequence Data; Muscle contraction; Muscle Contraction - drug effects; Myotropin; Neuropeptides - isolation & purification; Neuropeptides - pharmacology; Orthoptera; Proteins; Sequence Homology, Nucleic Acid; Substance P; Tachykinin; Tachykinins; Locustatachykinin; Myotropin; Insect neuropeptide; Substance P; Homology; Locusta migratoria; Tachykinin; Muscle contraction; Insecta; Orthoptera; HPLC chromatography; Neuropeptide; Acrididae; Characterization; Molecular evolution; Arthropoda; Acridoidea; Invertebrata; Comparative study

Two myotropic peptides termed locustatachykinin I (Gly-Pro-Ser-Gly-Phe-Tyr-Gly-Val-Arg-NH 2) and locustatachykinin II (Ala-Pro-Leu-Ser-Gly-Phe-Tyr-Gly-Val-Arg-NH 2) were isolated from brain-corpora cardiaca-corpora allata-suboesophageal ganglion extracts of the locust, Locusta migratoria. Both pepti...