Anticancer Water‐Soluble Organoruthenium Complexes: Synthesis and Preclinical Evaluation - Azmanova, Maria; Rafols, Laia; Cooper, Patricia A.; Seaton, Colin C.; Shnyder, Steven D.; Pitto‐Barry, Anaïs (Chembiochem : a European journal of chemical biology, 2022)
Keywords: Antineoplastic Agents - pharmacology; Apoptosis; Biocompatibility; bioinorganic chemistry; Cancer; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemical Sciences; Coordination Complexes - toxicity; Coordination compounds; Cytotoxicity; Drug Screening Assays, Antitumor; Female; half-sandwich complexes; Humans; In vivo methods and tests; in vivo evaluation; Life Sciences; Ligands; Lung cancer; Lung Neoplasms; Medicinal Chemistry; Metal complexes; metallodrugs; Organophosphorus Compounds; Organoruthenium complexes; Ovarian cancer; Ovarian Neoplasms; Phosphine; phosphine ligands; Phosphines; Prostate; Prostate cancer; Reactive Oxygen Species; Ruthenium; Ruthenium - pharmacology; Ruthenium compounds; Synthesis; Toxicity; Tumor cell lines; Tumors; Water; Xenografts; Xenotransplantation; in vivo evaluation; half-sandwich complexes; metallodrugs; phosphine ligands; bioinorganic chemistry; phosphines; ligands; antineoplastic agents; drug screening assays; in vivo evaluation; lung neoplasms; antitumor; water; organophosphorus compounds; ovarian neoplasms; ruthenium; carcinoma; tumor; reactive oxygen species; non-small-cell lung; female; coordination complexes; humans; cell line