pH-Responsive Shrinkage/Swelling of a Supramolecular Hydrogel Composed of Two Small Amphiphilic Molecules

• Published in: Chemistry : a European journal Vol. 11; no. 4; pp. 1130 - 1136
• Main Authors: Zhou, Shan-Lai, Matsumoto, Shinji, Tian, Huai-Dong, Yamane, Hiroki, Ojida, Akio, Kiyonaka, Shigeki, Hamachi, Itaru
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 04.02.2005; WILEY‐VCH Verlag; Wiley
• Subjects: carboxylic acids; Chemistry; Chemistry, Multidisciplinary; copolymerization; gels; pH response; Physical Sciences; Science & Technology; supramolecular chemistry; copolymerization; GELATION PROCESS; pH response; MEMORY; gels; carboxylic acids; PHASE-TRANSITION; DESIGNED PEPTIDE; WEIGHT HYDROGELATORS; CHIRALITY; supramolecular chemistry; REVERSIBLE HYDROGELS; DERIVATIVES; POLYMER GELS; GLYCOSYLATED AMINO-ACID

A pH‐responsive volume‐change function was successfully introduced into a supramolecular hydrogel that contained GalNAc‐appended (GalNAc=N‐acetylgalactosamine) glutamate ester 1 by the simple mixing of it with an appropriate amount of 2 a or 2 b amphiphilic carboxylic acid. In the 1:1 mixture (1:2),...